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Post-Menopausal Use of Hormone Replacement Therapy Increases Ovarian Cancer Risk
"The increase in risk was found regardless of the hormone dose or formulation, whether hormones were taken by mouth, transdermal patch, or vaginally, or whether the treatment included just estrogen or estrogen and progestin, the researchers say."
The trend for ovarian cancer incidence in the U.S. does show a decline since the first study reported risk of HRT and cancer in women